RISK assessment of chemicals integrating Human centric Next generation Testing strategies promoting the 3Rs

general assembly
RISK-HUNT3R General Assembly (Feb 13-17, 2023), Egmond.

This 5-year project runs from June 2021 with a funded budget of €22.9M given by the European Commission’s Horizon 2020 programme. RISK-HUNT3R builds on the outcomes of the Horizon 2020 toxicological flagship project EU-ToxRisk, which ended in 2021.

RISK-HUNT3R is one of the three projects constituting the research cluster ASPIS (“Animal-free Safety assessment of chemicals: Project cluster for Implementation of novel Strategies”). Together with the projects ONTOX and PrecisionTOX, this represents Europe’s €60M effort towards the sustainable, animal-free and reliable chemical risk assessment of tomorrow.

The project is aiming to develop a new modular framework for animal-free next generation risk assessment (NGRA) driven by world-leading experts from various disciplines. Its vision is to combine human exposure scenarios, in vitro hazard assessment, and NAM-based toxicokinetic and toxicodynamic testing (Non-Animal test Methods, either in silico or in vitro), followed by integrative risk assessment via computational approaches and decision-making based on weight of evidence.

Academic researchers, regulators, and safety scientists from industry aim to foster regulatory acceptance and direct practical application of NGRA in line with the Green Deal of the European commission. The project gathers a total of 37 European partners from 11 countries.

For more information about Risk Hunt3r project please visit: https://www.risk-hunt3r.eu/