Past projects

eTRANSAFE Enhancing Translational Safety Assessment through Integrative Knowledge Management.
eTRANSAFE was a 40 Million EUR European project for new drug safety assessment and integrative data analysis research.

The five-year project aimed to develop an advanced data integration infrastructure together with innovative computational methods to improve the security in drug development process.

EU-ToxRisk An Integrated European Flagship Programme Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st century.
The vision of EU-ToxRisk was to drive the required paradigm shift in toxicological testing away from ‘black box’ animal testing towards a toxicological assessment based on human cell responses and a comprehensive mechanistic understanding of cause-consequence relationships of chemical adverse effects.

This project was focused on two areas: repeated dose systemic toxicity, using the lung, kidney, liver and nervous system as examples of potential target organs; and developmental and reproductive toxicity.

eTOX In silico predictions of in vivo toxicity endpoints for novel drug candidates.
The eTOX project as IMI consortium has been completed with the accomplishment of an effective synergic sharing of historical toxicological data within the pharmaceutical industry.

It created a series of models to support toxicity predictions. Both data and models are integrated in the platform developed in the project, the eTOXsys™, which is a powerful system to access the eTOX data and the predictive models.

Biopsycho Development of novel antipsychotic drugs using advanced technologies in a multidisciplinary environment
The Biopsycho project was a coordinated research project aimed to the development of novel strategies for the discovery of antipsychotic drugs.